Small ruminant lentivirus infections and diseases
نویسندگان
چکیده
منابع مشابه
An insight into a combination of ELISA strategies to diagnose small ruminant lentivirus infections.
A single broadly reactive standard ELISA is commonly applied to control small ruminant lentivirus (SRLV) spread, but type specific ELISA strategies are gaining interest in areas with highly prevalent and heterogeneous SRLV infections. Short (15-residue) synthetic peptides (n=60) were designed in this study using deduced amino acid sequence profiles of SRLV circulating in sheep from North Centra...
متن کاملSmall ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes
Small ruminant lentiviruses (SRLVs) are prevalent in North American sheep and a major cause of production losses for the U.S. sheep industry. Sheep susceptibility to SRLV infection is influenced by genetic variation within the ovine transmembrane 154 gene (TMEM154). Animals with either of two distinct TMEM154 haplotypes that both encode glutamate at position 35 of the protein (E35) are at great...
متن کاملMannose receptor may be involved in small ruminant lentivirus pathogenesis
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) expression (transcript levels) and proviral load in virus target tissues (lung, mammary gland, CNS and carpal joints). Control sheep were SRLV-seropositive asymptomatic (n = 3)...
متن کاملSmall ruminant lentivirus genotype E is widespread in Sarda goat.
The highly divergent SRLV genotype E has recently been characterized in Italy as a low pathogenic caprine lentivirus in the Roccaverano breed. The availability of a genotype specific diagnostic test based on a comparative assay, using a combination of genotype specific recombinant antigens allows a wide serosurvey in other goat populations. The island of Sardinia still has the highest small rum...
متن کاملImmunogenetics of Small Ruminant Lentiviral Infections
The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed ligh...
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ژورنال
عنوان ژورنال: Veterinary Microbiology
سال: 2015
ISSN: 0378-1135
DOI: 10.1016/j.vetmic.2015.08.007